Posted by Elizabeth on December 31, 2000, at 0:06:29
In reply to Re: Dilated pupils caused by TCAs?? » PhoenixGirl, posted by Sunnely on December 4, 2000, at 20:08:23
> Indeed, tricyclic antidepressants (TCAs) such as desipramine (Norpramin) can cause pupils to dilate. This is due to their anticholinergic effect.
Desipramine doesn't have much in the way of direct anticholinergic activity, but the NE uptake inhibition might have the same effect.
BTW, I've heard that belladonna -- the plant that atropine and scopolamine come from -- got its name because dilated pupils were regarded as a sign of beauty (and in particular, that Italian prostitutes used to use atropine eyedrops). Urban legend?
poster:Elizabeth
thread:49892
URL: http://www.dr-bob.org/babble/20001130/msgs/50627.html