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Re: Zyprexa, any insider info? - Cam, Chris, All » Greg

Posted by Cam W. on October 17, 2000, at 21:09:22

In reply to Re: Zyprexa, any insider info? - Cam, Chris, All, posted by Greg on October 17, 2000, at 7:39:48

> Cam you mention a possible caustic effect if the Zy gets into your eyes. Could this be a possible cause for a mild comeback of my Acid Reflux? Chris, have you experienced this at all?
>

Greg - Good question. It sounds plausible, but the reflux is probably due some receptor either causing a leaky (or relaxed) pyloric valve (the valve at the entrance to the stomach that keeps the food in the stomach) or causing excess acid production. Then again, it could be a number of things, like involuntary suppression of blue &/or green flames (sorry all, an inside joke).

It probably wouldn't be the Zyprexa causing the burning. The burning is from the refluxed stomach acid. Most people can even take dissolved Zyprexa without stomach upset. I have had a few people complain of stomach upset, but it is usually a start-up side effect. The Zyprexa powder burns sensitive tissues (esp. the eyes). I don't really think it is too caustic to mucous membranes, either (in most people).

I believe that the Neurontin™ (gabapentin) or even Tegretol™ (carbamazepine) would cause more dyspepsia than the Zyprexa. Let's just split the difference and say that all the meds contribute to the reflux (not a scientific answer, but an easier answer that just might be correct - then again, maybe not). Almost every oral drug monograph lists some form of stomach upset as a side effect.

Monitor your tummy status over the next couple of weeks and report back.
Good luck - Cam


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poster:Cam W. thread:46233
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