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Re: Wellbutrin: How the hell does this stuff work?

Posted by salarmy4me on October 14, 2000, at 4:06:08

In reply to Wellbutrin: How the hell does this stuff work?, posted by JackD on October 14, 2000, at 0:43:41

> Sorry to beat this Wellbutrin thing to death, but I haven't been able to find any real facts about how/what it does exactly. I've read it's a weak reuptake inhibitor of Seratonin and Norepinephrine, and also (even weaker) Dopamine. However, I've also read that these reuptake properties are only significant at enormous doses, like maybe 600mg a day.
>
> I've also read a theory that it modulates norepinephrine flow in certain parts of the brain. This sounds like it's on the right track.
>
> I just tried Edronax, which raises Norepinephrine levels, with no where near the level of help Wellbutrin provided. In fact it did nothing but wake me up a little. So I guess I agree that Wellbutrin does more than just raise NE levels.
>
> Does anyone know any info about Wellbutrin's method of action? Or does anyone at least know some good places to look? Thanks guys.

http://www.rxlist.com/cgi/generic/buprop_cp.htm


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URL: http://www.dr-bob.org/babble/20001012/msgs/46324.html