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Re: atypical depression treatment? - jzp and noa

Posted by SLS on July 1, 2000, at 14:57:28

In reply to Re: atypical depression treatment? - jzp and noa, posted by Noa on July 1, 2000, at 14:00:16

> Scott, I really don't know if it is more common in one type of depression or the other, but I do know that some of the symptoms of hypothyroid overlap with those of atypical depresseion:

> fatique
> sluggishness
> sleepiness
> weight gain
> lack of motivation
> feeling of heaviness in the limbs

> So, especially with women, who are more prone to hypothyroid (though not exculsively a women's problem), I believe that with atypical depresion, hypothyroidism should be looked into.

> I would guess that quite often, both an endocrine approach and a psychopharm approach might be needed, but for many people with difficult to treat chronic depression, who also have subclinical hypothyroid, treating the hypothyroid aggressively is key to getting a good response to the antidepressants.


Noa - thanks for helping out here.

I forgot to mention that thyroid hormone is also used to augment antidepressants in the absence of abnormally low levels in the body. Blood levels of 150% of normal are often needed to produce a response. I found something today that indicated that this strategy is also effective for treating bipolar depression. In the studies cited, T4 was used.


- Scott

 

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