Posted by Scott L. Schofield on March 23, 2000, at 7:16:08
In reply to Re: Paxil and TCAs, posted by Cam W. on March 22, 2000, at 21:06:00
>
> Russ - There is a risk of serotonin syndrome when combining SSRIs with TCAs. I know it has been done using low doses of both, but this should only be done under the close supervision of your physician. Personally, I would not use both of these drugs together. - Cam W.
Is there some greater risk with using Prozac in such a combination as opposed to the other SSRIs.
I had been on relatively high doses of Paxil and Norpramin (desipramine) in combination with no ill effects. Combining a TCA with an SSRI is not an uncommon practice here in the US. Perhaps there is a greater risk of serotonin syndrome with using one of the more serotonergic tertiary TCAs, but I haven't heard anything that would contraindicate such a combination. Anafranil (chlomipramine) is the exception, as usual.
- Scott- Scott
poster:Scott L. Schofield
thread:27872
URL: http://www.dr-bob.org/babble/20000321/msgs/27923.html